Absolutely!
With MCN's there is no folding or "oragami", no pins, you don't even have to use covers if you use pocket nappies or all in ones.
One of the most common things I hear also is that MCN's are more absorbant that flats and of course with many MCN's you can change the absorancy without necessarily adding bulk. Which of course brings up the point that most MCN's are not as bulky as flats.
And of course we can't forget the cute factor!